In fact, China has long put forward the requirement of testing the TOC of water for injection. Because when the TOC in pharmaceutical water is very low, it indicates that the microbial content in the water is low, which can cause certain harm to the human body. Therefore, the purpose of detecting the TOC content in water for injection is also to enhance the safety of the injection solution! Now, let’s take a look at the TOC detection issues of water for pharmaceutical injection together with the editor.

We know that there are generally four basic types of pollutants in water: organic matter, inorganic matter, particles and microorganisms. The water quality analyzers used for detecting the content of different pollutants also vary. To detect the content of TOC in water, the TOC-8000-TOC online analyzer can be used, and the method employed is the non-dispersive infrared (NDIR) colorimetric method.

What will happen if the TOC content in water for injection is too high? What if it is not tested?

If the TOC content in water for injection is too high, it will cause bacteria and microorganisms to carry out subsequent production and also reduce the system function of pure water. If you don’t conduct tests on it, you won’t be able to know whether the medicine has been contaminated, nor will you know the reason or when it was contaminated. Moreover, the filtration device of the pure water system needs to be replaced, and there are dead corners in the management design where microorganisms grow, which you are unaware of. Additionally, the newly introduced impurities have not passed the verification.