First, it is necessary to clarify the definition of extraction-based pharmaceutical manufacturing. This process refers to a pharmaceutical production engineering approach that involves extracting and purifying biologically active primary substances from raw materials via biochemical, chemical, or physical methods. The present paper focuses on the wastewater testing protocols for extraction-based pharmaceutical facilities.

For wastewater discharge from such facilities, regulatory requirements including emission limits, monitoring and control specifications, and standard implementation and supervision must adhere to relevant statutory provisions. These standards are applicable to wastewater management in the extraction-based pharmaceutical industry, covering tasks such as environmental impact assessment, design of environmental protection infrastructure, and other wastewater treatment management activities. Key questions to address include:

What are the Wastewater Monitoring Points in Pharmaceutical Facilities? And What are the Corresponding Monitoring Indicators?

1.Monitoring Site Placement for Extraction-Based Pharmaceutical Facilities  

All extraction-based pharmaceutical facilities are required to install monitoring points at the following locations:

-Total wastewater discharge outlet;

-Domestic sewage discharge outlet (where biological sewage is discharged independently into the external environment);

-Stormwater discharge outlet.

2.Specific Monitoring Indicators  

Monitoring indicators vary by discharge outlet, as analyzed below:

a) Total wastewater discharge outlet: Total phosphorus (TP), total nitrogen (TN), ammonia nitrogen (NH₃-N), chemical oxygen demand (COD), total organic carbon (TOC), acute toxicity, chroma, suspended solids (SS), and pH value.

b) Domestic sewage discharge outlet: Animal and vegetable oils, flow rate, pH value, TP, and TN.

c) Stormwater discharge outlet: pH value, COD, NH₃-N, and SS.

In summary, common wastewater monitoring indicators across all outlets include pH value, SS, TP, TN, and NH₃-N—these are standard parameters mandatory for all wastewater testing. Regarding instrumentation for these measurements, Hangzhou Mudi recommends the use of single-parameter water quality analyzers. For instance, the TOC-8000 Online TOC Analyzer is specifically designed to detect TOC content in wastewater, serving as a dedicated tool for this parameter.